Motif ID: ELK1,4_GABP{A,B1}.p3

Z-value: 3.902


Transcription factors associated with ELK1,4_GABP{A,B1}.p3:

Gene SymbolEntrez IDGene Name
ELK1 2002 ELK1, member of ETS oncogene family
ELK4 2005 ELK4, ETS-domain protein (SRF accessory protein 1)
GABPA 2551 GA binding protein transcription factor, alpha subunit 60kDa
GABPB1 2553 GA binding protein transcription factor, beta subunit 1

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
GABPB1chr15_-_48434567-0.421.1e-01Click!
GABPAchr21_+_26029602-0.273.0e-01Click!
ELK4chr1_-_2038686220.155.7e-01Click!
ELK1chrX_-_473949370.107.1e-01Click!


Activity profile for motif ELK1,4_GABP{A,B1}.p3.

activity profile for motif ELK1,4_GABP{A,B1}.p3


Sorted Z-values histogram for motif ELK1,4_GABP{A,B1}.p3

Sorted Z-values for motif ELK1,4_GABP{A,B1}.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of ELK1,4_GABP{A,B1}.p3

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_50318801 5.088 IKZF1
IKAROS family zinc finger 1 (Ikaros)
chr2_+_113648036 4.423 PSD4
pleckstrin and Sec7 domain containing 4
chr12_-_53153639 4.219 NM_144594
GTSF1
gametocyte specific factor 1
chr12_-_53153613 4.183 GTSF1
gametocyte specific factor 1
chr9_-_133141726 4.030 NM_033387
FAM78A
family with sequence similarity 78, member A
chr19_+_17723285 3.675 NM_001161359
NM_015122
FCHO1

FCH domain only 1

chr15_+_21361901 3.674 MKRN3
makorin ring finger protein 3
chr2_+_113648020 3.567 NM_012455
PSD4
pleckstrin and Sec7 domain containing 4
chr10_-_11976704 3.553 LOC219731
hypothetical LOC219731
chr7_+_106293112 3.472 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr7_+_106292932 3.443 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr1_+_20385164 3.363 NM_152376
UBXN10
UBX domain protein 10
chr19_+_10402334 3.248 NM_001111308
PDE4A
phosphodiesterase 4A, cAMP-specific
chr22_+_20350272 3.233 NM_014337
NM_148175
NM_148176
PPIL2


peptidylprolyl isomerase (cyclophilin)-like 2


chr7_+_106292975 3.200 PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr13_-_45654296 3.150 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr16_+_29581783 3.129 NM_001030288
SPN
sialophorin
chr11_-_57038891 3.077 NM_001198810
SLC43A1
solute carrier family 43, member 1
chr3_+_47004457 3.060 NBEAL2
neurobeachin-like 2
chr7_+_6583560 3.032 NM_001134387
NM_001134388
NM_001134389
NM_018106
ZDHHC4



zinc finger, DHHC-type containing 4




Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 87 entries
enrichment   p-value GO term description
2.04 1.87e-08 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.04 1.87e-08 GO:0000398 nuclear mRNA splicing, via spliceosome
2.03 1.09e-04 GO:0042254 ribosome biogenesis
2.01 3.55e-08 GO:0000375 RNA splicing, via transesterification reactions
2.01 4.02e-02 GO:0022618 ribonucleoprotein complex assembly
1.99 1.54e-07 GO:0022613 ribonucleoprotein complex biogenesis
1.98 2.48e-02 GO:0006364 rRNA processing
1.93 4.87e-07 GO:0071843 cellular component biogenesis at cellular level
1.93 4.39e-02 GO:0016072 rRNA metabolic process
1.90 3.81e-02 GO:0006414 translational elongation
1.77 5.01e-07 GO:0008380 RNA splicing
1.77 3.06e-03 GO:0043687 post-translational protein modification
1.75 1.77e-04 GO:0071156 regulation of cell cycle arrest
1.74 2.40e-03 GO:0034470 ncRNA processing
1.73 5.24e-09 GO:0016032 viral reproduction
1.73 6.78e-04 GO:0000075 cell cycle checkpoint
1.71 8.23e-03 GO:0006260 DNA replication
1.68 2.18e-05 GO:0006412 translation
1.65 1.86e-06 GO:0006397 mRNA processing
1.65 8.94e-04 GO:0034660 ncRNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 36 entries
enrichment   p-value GO term description
2.25 7.47e-03 GO:0035770 RNA granule
2.09 1.54e-03 GO:0071013 catalytic step 2 spliceosome
1.93 8.07e-05 GO:0005681 spliceosomal complex
1.88 2.11e-19 GO:0030529 ribonucleoprotein complex
1.75 6.22e-03 GO:0000151 ubiquitin ligase complex
1.74 5.21e-13 GO:0005730 nucleolus
1.73 4.92e-04 GO:0005840 ribosome
1.57 1.24e-02 GO:0016604 nuclear body
1.51 9.74e-26 GO:0031981 nuclear lumen
1.49 5.78e-29 GO:0044428 nuclear part
1.48 2.78e-29 GO:0070013 intracellular organelle lumen
1.47 3.74e-15 GO:0005654 nucleoplasm
1.46 5.76e-28 GO:0031974 membrane-enclosed lumen
1.46 3.38e-27 GO:0043233 organelle lumen
1.39 6.52e-05 GO:0044451 nucleoplasm part
1.39 1.87e-03 GO:0005694 chromosome
1.37 3.24e-02 GO:0044427 chromosomal part
1.32 1.59e-11 GO:0005829 cytosol
1.31 2.25e-15 GO:0043228 non-membrane-bounded organelle
1.31 2.25e-15 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
enrichment   p-value GO term description
2.76 4.42e-02 GO:0019843 rRNA binding
1.84 7.72e-05 GO:0008168 methyltransferase activity
1.79 2.88e-04 GO:0016741 transferase activity, transferring one-carbon groups
1.71 1.67e-02 GO:0003735 structural constituent of ribosome
1.56 9.59e-13 GO:0003723 RNA binding
1.31 7.41e-19 GO:0003676 nucleic acid binding
1.31 1.53e-02 GO:0019899 enzyme binding
1.23 2.79e-06 GO:0003677 DNA binding
1.22 1.56e-04 GO:0008270 zinc ion binding
1.18 3.25e-19 GO:0005515 protein binding
1.17 1.06e-02 GO:0000166 nucleotide binding
1.08 1.82e-11 GO:0005488 binding